Resumen
The aim of this systematic review is to determine the effectiveness of manual therapy applied alone on pain,
function, symptom severity, nerve conduction and strength in people with carpal tunnel syndrome. We searched
MEDLINE, WOS, SCOPUS, PEDro, CENTRAL, LILACS and Epistemonikos. Twelve studies met the eligibility criteria
and nine were included in the quantitative synthesis. Pain had a standardized mean difference of - 1.83 (95% CI = -
2.62, - 1.03, p = < .00001), function a mean difference of -0.88 (95% CI = - 1.05, - 0.71, p = < .00001), symptom severity
a mean difference of - 0.94 (95% CI = - 1.58, - 0.30, p = .004), sensory conduction velocity a mean difference of 7.46 (95%
CI = - 0.11, 14.98, p = .05), motor conduction velocity a mean difference of 1.85 (95% CI = 0.68, 3.01, p = .002), motor
latency a mean difference = - 0.57, (95% CI = - 0.96, - 0.17, p = .005), grip strength a mean difference = - 0.24, 95% CI
= - 2.22, 1.74, p = .81) and grip strength a mean difference = 0.21 (95% CI = - 0.42, 0.83, p = .52). Finally, it is concluded
that manual therapy applied alone is an effective shortterm option for people with mild to moderate carpal tunnel
syndrome.

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